Abstract. Introduction. Training of specialists and updating educational programs of higher education, based on regional economy’s needs, are required for solving problems of region’s sustainable development during the transformation of economic system. Purpose. The purpose of the research is developing methodological approaches to the formation of educational programs in educational process reengineering context. Materials and methods. The methodological basis of the research is systems approach provisions. The systematic approach makes it possible to comprehensively assess training specialists possibilities at specific characteristics level, to identify problems of entry, process and exit, taking into account both internal and external environment of university. During the research, formal-logical and general scientific methods are used, including abstract-logical, induction, deduction, synthesis, modeling. The research is based on the principles of objectivity in considering the process of training qualified specialists, coherence, synergy, and holism. Research results, discussion. The solution of the problem of systemic development of regions and innovative sectors of economy depends on human capital, qualified personnel training. This article considers the requirements of the Federal State Educational Standard 3++ in the direction of training 03.03.01 Economics. The importance of development of basic professional educational programs is substantiated, taking into account the requirements of educational regulatory documents, professional standards, employers. The necessity of combining the educational program with goals and objectives of national projects, the needs of regional economy staffing is shown. Conclusion. The proposed algorithm for developing an educational program in accordance with regulatory documents requirements and a process approach determines the methodological features of the creation and implementation of educational programs, taking into account the opinion of employers, requirements of the regional labor market, provides an opportunity to form practice-oriented education model.